Synthesis on nontoxic, antibody-bindingEscherichia coliheat-stable enterotoxin (STa) peptides
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چکیده
منابع مشابه
Structural Characterisation of the E. coli Heat Stable Enterotoxin STh
E. coli heat stable enterotoxin STa is an agonist of the membrane guanylate cyclase C whose endogenous ligands are the peptide hormones guanylin and uroguanylin. Whereas these peptides contain only two disulfide bonds, STa is stabilized by one additional disulfide bridge. We chemically synthesized the enterotoxin STh that originates from the E. coli strain found in humans, and we determined its...
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I t has long been recognized that preexisting antibody, either endogenously formed, or passively administered near the time of the injection of the corresponding antigen, can affect the subsequent antibody response. An excess or, in some cases, even an equivalent amount of passively administered antibody can partially or completely inhibit the primary response in a previously unchallenged anima...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 1988
ISSN: 0378-1097,1574-6968
DOI: 10.1111/j.1574-6968.1988.tb02792.x